Sentence examples for modifies the phenotype from inspiring English sources

Rescue experiments are inadequate here, because even a modest increase in AR expression modifies the phenotype of the prostate tumor cells [6].

For example, concomitant α thalassemia modifies the phenotype of sickle cell anemia and β thalassemia.

This finding indicates that the C57BL/6J strain background modifies the phenotype of the Bcl2l2 GtROSA41Sor mutation.

Further evidence is required to substantiate the hypothesis proposed by Lange et al. (2014), that R32450W/R279W modifies the phenotype of HMERF.

We recently reported that proteasome inhibition (PI) profoundly modifies the phenotype of human dermal fibroblasts by reducing type I collagen synthesis and increasing MMP-1 production [ 21].

Here we demonstrate that BCL2 not only modifies the phenotype of OPMD model mice, but also regulates a central pathway of myofibre death in OPMD.

AHI1 seems to act as a modifier of CEP290[ 133] and NPHP1[ 134], and PDZD7 can modify the phenotype in Usher syndrome patients who have a homozygous USH2A mutation [ 135].

Gene transfer is a therapeutic strategy which uses genetic information, usually in the form of DNA, to modify the phenotype of cells.

It is possible that the manifestation of the most severe phenotype is due to an unlikely combination of genetic and non-genetic factors (endogenous or environmental factors, which may be precipitating or modifying the phenotype).

These results collectively indicate that microenvironmental factors can uniquely modify the phenotype of differentiated recruited monocytes inducing marked changes in mRNA levels and also in miRNA expression and kinetics that may modulate the remarkable flexibility of monocyte responses to specific environmental cues.

In a deficiency screen for dominant modifiers 13 out of 109 assayed deficiencies (covering around a 55% of the genome), visibly modified the phenotype being most of them dominant suppressors (Table S2).