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An example is the way that hormones such as insulin, testosterone, and growth hormone are produced in one part of the body, and travel to other parts where they interact with "receptors" in a way that modifies the activities of various other structures.
Furthermore, PCSK9 enhances the intracellular expression of the apoprotein B48 (apoB48) [ 98, 135] and modifies the activities of the HMG-CoA reductase (decreased), the Acyl-CoA-Cholesterol-Transferase (ACAT, decreased) [ 98] and the microsomal transfer protein (MTP, increased) [ 98].
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Immobilization modifies the activity, selectivity, and equipped permanence of enzymes.
The input modifies the activity of the network and the strengths of various connections in a distributed way, such that the subsequent behavior of the network effectively implements inferential question-answering.
However, EYA1 interacts with and modifies the activity of SIX1, which was identified in our analyses.
The idea that the lipid environment modifies the activity of membrane proteins is not new.
Each of these modifications modifies the activity of the target protein and thus its function in a signaling pathway.
Besides, SUMO modifies the activity and/or localization of proteins with important roles in cell proliferation, differentiation, and apoptosis [ 74].
Actually, it is not known if the absence of this cystein-rich domain compromises or modifies the activity of the receptor.
Aspirin acts by irreversibly inhibiting cyclooxygenase (PTGS, previously COX-1) and modifies the activity of PTGS-2 required for the synthesis of prostaglandins.
Protein nitration is a posttranslational modification caused by nitric oxide (NO) derived oxidants that frequently modifies the activity of the target molecule [ 15, 16].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com