Sentence examples for modifies methylation of from inspiring English sources

We hypothesized that tobacco smoking modifies methylation of the genes identified for CAD by genome-wide association study (GWAS).

Morpholinos are not known to modify methylation of DNA.

In rats, maternal exposure to BPA modified methylation of the metastable loci Avy and CapbIAP [ 97].

In vivo model studies have shown that genistein can modify methylation levels in the prostate of mice [ 156] and that, overall, epigenetic changes could be detected by genistein treatment; however, the results on the anticancer activity of this compound were contradictory.

Jmjd3 is essential for the gene expression of homeobox and bone morphogenetic proteins by modifying methylation.

To identify novel methylated TSGs, we employed a strategy of modified methylation-sensitive representational difference analysis (MS-RDA), using uracil-DNA glycosylase-based digestion during MS-RDA (Sugai et al, 1998; Kaneda et al, 2003), for DNA samples of the wild-type and DNA methyltransferases (DNMT1 and -3B) DKO of HCT116 (Rhee et al, 2002).

The ECL biosensing electrode was fabricated by self-assembling a design of 5′-thiol modified methylation-responsive hairpin-capture DNA probe on the surface of a gold electrode.

Interestingly, an epigenetic alteration and a single nucleotide change that modify the methylation of a CpG were found at the same location in two different samples.

In higher eukaryotes, mRNA and small nuclear RNA (snRNA) 5′ ends are further modified by methylation of the ribose on the first and second transcribed nucleosides (that is, cap1 and cap2, respectively)6.

A DNA methylation inhibitor modified the methylation of CGIs and altered the isoform-specific expression of SHANK3 in cultured cells.

Many viral RNAs are modified by methylation of the N6 position of adenosine (m6A).