Sentence examples for modifies expression of from inspiring English sources

Previous studies have shown that combination therapy modifies expression of hundreds of genes in vitro and in vivo.

p16 forms a physical complex with HIF-1α and modifies expression of VEGF in breast cancer cells.

TCDD alters glucose and lipid metabolism in mice (Dalton et al. 2001), modifies expression of genes related to insulin transport and signaling pathways in human adipose tissue (Fujiyoshi et al. 2006), and produces oxidative stress at high concentrations (Kern et al. 2002; Matsumura 2003).

We examined the effect of maternal caloric excess on offspring and found that a high-sugar maternal diet alters body composition of larval offspring for at least two generations, augments an obese-like phenotype under suboptimal (high-calorie) feeding conditions in adult offspring, and modifies expression of metabolic genes.

Functional delivery of oligonucleotides to epidermis in order to edit or modify expression of mutant genes.

Signal transduction leads to modifying expression of defense-related genes and defense mechanisms against BPH, including sieve tube sealing, production of secondary metabolites, and induction of proteinase inhibitor.

This observation suggests that modified expression of a relatively small subset of ROS-associated or -induced genes may suffice for a degree of tolerance to ROS.

Firstly, FGFR3 activating mutations affect input signals (modified expression of other growth factors and membrane bound receptors, biochemical properties of the ECM).

However, GGTI-298 alone (10 µM) did not significantly modify expression of MHC-I and in particular HLA-A0201 (Figures 3A and 3B).

In turn, modified expression of several of these molecules, including CaMK [2], AMPK [3], [4], PGC1α[5], [6] and β[7], and PPARδ [8], directly alters metabolic outcomes in mice including adiposity, glucose tolerance, oxidative capacity, and endurance (or resistance to fatigue).

The RT-qPCR analysis detected two clusters (Dio3, Rtl1, Dlk1 on chromosome 12 and Slc22a1, Slc22a2, Slc22a3 on chromosome 17) displaying modified expression of genes involved in regulation of homeostasis.