Sentence examples for modifies binding of from inspiring English sources
We predict that a differentiated G ↔ A SNP modifies binding of miR-155, a well-known regulator of immune function (O'Connell et al. 2009).
Polysaccharides are known to modify binding of proteins at interfaces and this paper describes studies of these interactions and how they are modified by pH.
Mutations in the protease flap region are recognized as critical for modified binding of a number of PIs.
Changes of epigenetic marks, such as DNA methylation, can affect the chromatin structure and modify binding of transcription factors and gene expression.
Several studies have shown that the -31C/G polymorphism was associated with modified binding affinity of the CDE/CHR repressor, changed activity of the promoter, and subsequently resulted in different expression levels of BIRC5 mRNA and protein in normal and cancer cells.
As a consequence, both increased expression of AP-1-dependent target genes by the activating transcription factors c Jun/c Fos and modified binding activity of the resulting AP-1 complexes via the action of deactivating JunB and JunD may contribute to the pathogenesis of RA.
This strategy modifies the binding of components of the spliceosome by high affinity hybridisation of small complementary (antisense) RNA oligonucleotides to specific pre-mRNA sequences.
Finally, if Ab deglycosylation only moderately alters antigen binding, it significantly modifies the binding of Fc γR on human cell lines.
This conformational change may modify the binding of renin/prorenin to its recently described renin receptor (Nguyen et al, 2002).
The change in dipole potential as a function of subphase concentration of tetraphenyl-boron was much larger for egg PC than for fluorinated PC monolayers, indicating that the fluorine atoms modified the binding of this hydrophobic anion.
The immunoreactivity assessed using the method described by Lindmo [23] (Figure 1B) was close to 80%, showing that the labeling did not modify the binding of B-B4 mAb to the CD138 antigen.
