Sentence examples for modifiers that contribute from inspiring English sources

Further, larger population studies will be required to confirm whether both these changes represent rare polymorphisms, low penetrance modifiers that contribute to ovarian cancer development and/or are direct pathological mutations.

Components of any of these pathways may represent second site genetic modifiers that contribute to the tissue- and cell type-specific variation of (CTG n CAG n TNR instability observed in mice and humans.

Our analysis demonstrated that dom modifiers are enriched for loci that contribute to the regulation of cell growth and proliferation, which is consistent with prior studies of dom function.

Phenotypes derived from such constructs allow screens for modifiers, thereby expanding the known set of genes that contribute to a pathway (Brand and Perrimon 1993; Rorth 1996).

Because the roX RNAs are necessary for exclusive X-localization of the MSL proteins, genetic modifiers of roX1 roX2 lethality may identify novel pathways that contribute to X-recognition.

These aberrant epigenetic modifiers have become new targets for drug design, because their inhibition can potentially reverse the altered epigenetic landscapes that contribute to the development of the leukemia.

Possibly that contributed to confusion.

So that contributed to it.

This finding suggests that modifier genes contribute to FPAH clinical expression.

This complexity is not surprising given that additional modifiers may contribute to the net effects of Hsp90 inhibition.

Recently, several next-generation tumor sequencing projects have identified frequent mutations in chromatin remodeling genes in a variety of entities, including medulloblastoma, supporting the hypothesis that these modifiers might contribute to the malignant progression of cancer [ 33, 34].