Sentence examples for modifiers of human from inspiring English sources

There are likely many more genetic modifiers of human longevity that remain to be discovered.

However, these variants have been mainly related to lipoprotein metabolism [20] [22], FOXO proteins [23], [24], and insulin/IGF-1 signaling [25] It is likely that many more genetic modifiers of human aging have yet to be discovered [25].

b) What are potential confounders or modifiers of human health risks (synergistic or antagonistic) at low-level exposure?

Among known genetic modifiers of human aging, only the APOE locus has been reproducibly associated with both lifespan and health span by GWAS (Deelen et al., 2011, 2014).

However, ITC experiments using chemical modifiers of human Keap1 have suggested that the overall affinity for binding of the Neh2 domain is unchanged [40].

In addition to lncRNAs, a second class of ncRNAs, miRNAs have been shown to be key modifiers of human disease and serve as biomarkers for disease states [3].

These findings render the human homologue, SIRT1, a very plausible candidate as a modifier of human life expectancy.

PGC-1α has also been identified as a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis [ 63].

It is possible that variable efficiencies of NMD can influence the clinical outcome of hereditary and acquired genetic disease and thus act as a genetic modifier of human genetic diseases.

We have shown here the first mutation in a K2P channel acting as a modifier of human cardiac arrhythmia providing evidence that K2P channels are important regulators of cardiac excitability.

In summary, we have carried out a thorough screen for modifiers of mutant human Htt aggregation using new models of HD established in cultured Drosophila cells and in the fly.