Sentence examples for modifiers of cancer from inspiring English sources

Genetic Modifiers of cancer risk in BRCA1/2 mutation carriers (GEMO): We wish to thank all the GEMO collaborating Cancer Genetics Network 'Groupe Génétique et Cancer' and Fédération Nationale des Centres de Lutte Contre le Cancer, France.

Germline genetics, gender and hormonal-signaling pathways are all well described modifiers of cancer risk and progression.

CIMBA is a collaborative group of researchers working on genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers.

The Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) is currently examining the role of various genetic modifiers of cancer risk in BRCA mutation carriers.

Stromal fibroblasts are one of the major stromal components and it is becoming increasingly clear that fibroblasts are also prominent modifiers of cancer progression [ 21].

There are published reports of genetic modifiers of cancer risk in mutation carriers (for example, variants in AIB1 in BRCA1; variants in RAD51, FGFR2 and MAP3K1 in BRCA2; and variants in TNRC9 in BRCA1 and BRCA2) [ 9- 13].

Recently, there is increasing evidence that fibroblasts are a prominent modifier of cancer progression [ 93, 94].

These antiangiogenic properties immediately excited interest in the potential of endostatin as a modifier of cancer biology.

In the under 51 years old they found a much larger fraction of patients harboring MDM2 SNP309G/G compared to the fraction of patients harbouring this SNP in the over 51 years old, supporting a role for this SNP as a modifier of cancer risk in BRCA1/2 mutation carriers.

We have identified additional genetic modifiers of breast cancer risk for mutation carriers among reported breast cancer susceptibility loci.

Such determinants would be potential modifiers of gastric cancer risk among individuals with H pylori infection and may suggest effective cancer prevention strategies.