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To our knowledge, this is the first Drosophila RNAi screen for modifiers of a mutant human aggregating protein.
Modifiers of a cancer phenotype may act either intrinsically or extrinsically on the salient cell lineage.
Proving which variants are actually playing as modifiers of a given condition is not a trivial issue [22].
Furthermore, it is difficult to plan a study design able to take into account all the potential confounders and effect modifiers of a plan's effectiveness.
Tara, a member of the trithorax group, was isolated in a screen for modifiers of a homeotic phenotype (Calgaro et al. 2002).
Thus, this preliminary screen for modifiers of a dom wing phenotype indicates that it is a reliable method to further dissect dom function.
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We conducted a screen for genetic modifiers of an Smn phenotype using the Exelixis collection of transposon-induced mutations, which affects approximately 50% of the Drosophila genome.
Last, DAGs are helpful for determining which factors may be confounders or effect modifiers of an association between exposure and outcome (VanderWeele and Robins 2007).
James Fenimore Cooper, in his 1841 "Deerslayer," had a character "almost livid with emotion," but never said what color that was; however, Walter Scott's 1814 use of the word as a modifier of a color -- his trembling lips are livid blue" -- suggests to me that the meaning was "pallid, ashen, leaden".
The nanostructure was then employed as the modifier of a carbon paste electrode.
To identify a quantitative modifier of a phenotype of interest, a cluster of test progeny is needed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com