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Thus, use of epigenetic modifiers may help to gain access to a vast repertoire of compounds that are either not produced or produced in minute undetectable quantities under normal fermentation conditions.
Further knowledge of treatment effect modifiers may help optimize treatment effects which, for commonly used interventions, are small [ 80- 82].
Lastly, clarity about which baseline characteristics are prognostic factors and which are potential treatment effect modifiers may help outline the best management strategy.
The causes of this gender difference are not certain, and further studies of this MEN1 mouse model for gender-specific gene modifiers may help to elucidate these.
The identification of second site genetic modifiers may help to explain the variability of (CTG n CAG n TNR instability patterns between tissues and individuals, and offer opportunities for prognosis and treatment.
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We hypothesized that assessing the gene expression of the chemotherapy response modifiers multidrug resistance gene 1 (MDR1) and excision repair crosscomplementing 1 (ERCC1) may help identify the group of patients benefiting from cisplatin-based adjuvant chemotherapy.
These opposing mechanisms, whereby alcohol may act as an effect modifier in the hypothesized causal association between insulin exposure and endometrial cancer risk, may help to explain some contradictory findings in the literature to date.
Quantitative examination of gene expression in Drosophila brains during aging may help to identify the genetic components of neuronal aging as well as genetic modifiers of neurodegenerative diseases.
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