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Moreover, the addition of four modifiers into the control asphalt binder can delay and weaken the aging and oxidation effect.
The separation of the parent drug and polar metabolites in one chromatographic run usually requires the use of gradient elution and often the addition of ionic modifiers into the mobile phase to increase the retention of polar conjugates [ 30].
We therefore decided to manipulate H3K9 modifications during de novo kinetochore assembly using a synthetic alphoid DNA array carrying multiple tet operator (tetO) sequences that allow the tethering of chromatin modifiers into the array as tet repressor (tetR) fusions (Nakano et al, 2008; Cardinale et al, 2009; Bergmann et al, 2011).
When tetracycline repressor fusion proteins were used to direct various chromatin modifiers into the centromeric chromatin, this revealed that excessive heterochromatin or excessive transcriptional activity within the centromere are incompatible with kinetochore assembly and propagation (Nakano et al., 2008; Cardinale et al., 2009; Bergmann et al., 2012).
The principle of this approach is based on the insertion of an amplified sequence carrying multiple tet operator (tetO) or lac operator (lacO) sequences into an ectopic chromosomal site that allows the tethering of chromatin modifiers into the array as tet repressor (tetR) or lac repressor (lacR) fusions.
Because MHC>>PAX7-FOXO1 expressisn is lethal, a typical forward genetic screen would normally require a multigenerational scheme to bring the MHC-Gal4 driver, UAS-PAX7-FOXO1 trandgene, and candidate modifiers into the same genetic background, a cumbersome and lengthy process that would need repeating for every candidate mutation-containing chromosome to be tested.
Similar(54)
The shift in the absorption edge in the modified semiconductor nanoparticles is attributed to the excitation of localized electrons from the surface modifier into the conduction band continuum states of the semiconductor particle [13].
Summit is no longer merely an attributive noun modifying meeting or conference; usage over 50 years has turned the modifier into that top-level conclave itself.
FTIR spectroscopy results showed that the addition of WMA modifiers into asphalt binder could delay and weaken the oxidation reaction of the binder which in turn improved the aging process.
The addition of 8% of the three different kinds of viscosity modifiers into A-type SBS modified asphalt resulted in a certain degree of improvement in its performance.
Table 9 shows that the addition of 8% of the three different kinds of viscosity modifiers into A-type SBS modified asphalt has a certain degree of improvement in its performance.
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