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In developing countries, infectious pressure might be one particular modifier of insulin resistance.
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Second, given the potentially harmful effects of insulin as well as its role as an effect modifier, we repeated our analyses excluding insulin users.
Other limitations include the single time of biologic sample collection, lack of data on other exposures, such as chlorinated naphthalenes, imprecise measures of insulin resistance and secretory capacity, and limited data on additional confounders and effect modifiers.
Think of insulin as a switch.
Severe diabetics require periodic injections of insulin.
For our insulin-producing bacteria, we would test whether the bacteria grows and the amount of insulin it produces.
This can then lead to the overproduction of insulin and finally insulin resistance.
These are all a result of insulin resistance and too much insulin.
Various parameters of insulin resistance were measured.
Age at first insulin prescription, sex, number of unique other drugs used in the year before start of insulin (excluding those prescribed for diabetes), number of hospitalisations in the year before start of insulin and calendar time were considered potential confounders or effect modifiers.
Dial your dose of insulin.
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