Sentence examples for modifier genes is from inspiring English sources

This finding suggests that each set of modifier genes is adapted to the gene complex in which it normally occurs and in which it probably evolved.

Already, great strides have been made to translate these early discoveries into clinical practice, and the characterization of novel mutations in chromatin modifier genes is rapidly accelerating.

Determining modifier genes is extremely important for understanding differences in both normal and disease phenotypes, and for designing potential therapeutic avenues for disease.

Background and Objectives: It is now generally admitted that penetrance of the common HFE p.C282Y/p.C282Y genotype is incomplete, and identification of modifier genes is the concern of a growing number of research projects.

Identification of mouse cancer modifier genes is a step toward understanding the genetic and biochemical mechanisms of inherited cancer predisposition.

The decision not to include any adjustment in these families for the effects of modifier genes is questionable.

Moreover, the admixture of ethnic groups plays an important role in the characterization of modifying effects, as modifier genes are diverse in different ethnicities and their complexity increases in ethnically admixed populations according to the extent of gene flow.

The effects of modifier genes are not carried to the offspring when members of different geographic races are crossed.

An NGS panel targeting the coding regions of hemoglobin genes and four modifier genes was designed.

Because of the great clinical variability between PXE patients the involvement of modifier genes was recently suggested.

Once the modifier genes that suppress mitochondrial dysfunction are identified, the door opens to new potential therapeutic targets, since these modifier genes are more amenable to administrate than the primary mutant mtDNAs.