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The results show that the combination of multi-wall carbon nanotubes and a modifier causes a dramatic enhancement in the sensitivity of FA quantification.
After 20% modifier, the continuous increase in the amount of the modifier causes a decrease of the peak current, because excessive coconut shell powder results in the decrease of conductivity of the modified electrode.
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Indeed, the Nnt mutation acts as a genetic modifier, causing mice lacking the mitochondrial matrix localized superoxide dismutase 2 to display a more severe phenotype in which they die during embryogenesis (Huang et al. 2006; Kim et al. 2010).
The observation that loss of chromatin modifiers causes strong phenotypes, which can often be interpreted as a consequence of transcriptional deregulation, provided further support.
To ensure that the disruption of collagen X function rather than presence of strain specific modifiers caused the variable skeleto-hematopoietic phenotype in the collagen X Tg and KO mice, we generated congenic Tg and KO lines by backcrossing greater then twelve generations into C57BL/6 and DBA/2J strains.
A subset of high-potency fascin-pathway modifiers caused overt cytotoxicity at the 50-μM concentration.
The disorder is caused by mutations in alpha-l-iduronidase, but the various mutations in the enzyme and unknown modifiers cause three different phenotypes, known, in descending order of severity, as Hurler's, Hurler-Scheie and Scheie's syndromes.
We found that the modifiers caused relatively small changes in net cellular uptake of the anticancer drugs, so that concentrations of omeprazole and chloroquine that inhibit uptake of anticancer drugs into endosomes probably cause redistribution of doxorubicin and mitoxantrone within the cell.
This threshold value is pivotal in determining whether the spread of a modifier allele causes the extinction of Wolbachia and was confirmed by simulation.
3 4 It has been proposed that in such families there is an additional genetic modifier which causes hearing loss in the absence of aminoglycosides.
Indeed, modeling of such scenarios frequently leads to the fixation of a nuclear inheritance modifier that causes switching from an ancestral biparental to a derived uniparental mode of inheritance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com