Sentence examples for modified tumor cells from inspiring English sources

Therapeutic vaccination of mice bearing melanoma tumors with our genetically modified tumor cells, via DOTAP/GM-CSF lipoplexes, results in >85% tumor growth inhibition.

The general conclusion drawn from experimental tumor models and for human cancer is, that although modified tumor cells were found to be partially effective in experimental models, it is still necessary to provide more data in order to determine the effective use of xenogenized human tumor cells for immunotherapy.

Injecting these cells into the mice represents an isogenic relationship between the host and the tumor cells, and allows the studies of molecularly modified tumor cells.

Using genetically modified tumor cells, we present evidence that the overexpression of WSX1 in two independent tumor models, such as aggressive Lewis Lung Carcinoma (LLC) and melanoma cell line AGS, promotes tumor growth independent of IL27 signaling.

In mouse models, prophylactic vaccines using GM-CSF modified tumor cells can engender protective immunity to delay tumor growth [ 21].

When vaccination strategies are employed (using modified tumor cells or dendritic cells, for example), generating sufficient numbers of CTL may be particularly difficult, even following booster vaccinations.

In this study, we developed an effective and gene modified tumor cell vaccine.

In fact, researchers have found that genetically modified tumor cell with secreted immune activating cytokines has the ability to enhance the immunogenic and induce systemic antitumor immune responses [ 9].

Until he was in his late 40s, Jorgensen had studied ways to modify tumor cells genetically to make them more vulnerable to ionizing radiation.

The need to modify tumor cells in order to render them more "immunogenic" was based on the assumption that normal, nonmodified tumor cells are non or weakly immunogenic and as such are unable to raise an efficient protective immune response.

This study examined if HAMLET interacts with and modifies tumor cell proteasomes.