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"These advancements have involved the editing of human somatic [non-reproductive] cells with the aim of repairing or eradicating a mutation that could cause disease or to engineer beneficial changes to allow cell therapy, for example in cancer, where an individual's immune cells might be modified to target cancerous cells," it says.
Spaced retrieval (SR) has recently been modified to target anomia in persons with aphasia (PWA).
Both of the above objections to direct reference theories of indexicals can easily be modified to target theories that say that the contents of expressions containing indexicals, in contexts, are merely intensions, rather than structured contents.
This approach could introduce an enriched potentially therapeutic subpopulation of autologous cells or of cells genetically modified to target specific macrophage pathways to ameliorate fibrosis induction or to induce fibrosis resolution.
The substrate recognition sequence of the trans-acting delta ribozyme, which was derived from the self-cleaving motif located on the antigenomic strand of the hepatitis delta virus genome, was modified to target T. gondii transcripts.
The fusion constructs may be modified to target other molecules to promote axonal regeneration and the concept may also be adapted to develop gene therapy strategies to treat other disorders.
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Nanoparticles can be modified to selectively target certain cells and thus optimize this balance of drug delivery to the target site versus non-targeted sites.
The rice microRNA, osaMIR528, was modified to specifically target either BdCESA4 or BdCESA7.
To promote drug targeting ability, protein nanoparticles have been chemically modified to incorporate targeting ligands that recognize specific cells and tissues.
17 Therefore, nanoparticles have been modified to include targeting ligands that interact specifically with targets such as growth factor receptors, 29, 40 tumor matrix proteins, 24, 37 signatures of the tumor-associated endothelium 4, 36 or combinations thereof.
These rules are modified to implement targeted mitigation strategies within the community, the effectiveness of which is evaluated (5 ).
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