Sentence examples for modified to bind from inspiring English sources

The rat theta-class glutathione transferase T2-2 (rGST T2-2) presents an ideal scaffold for the design of a novel GPX catalyst because it already binds GSH and contains a serine close to the substrate binding site, which can be chemically modified to bind selenium.

Structural analysis of the variant HEAT repeats in AlkD provides a rationale for how this protein scaffolding motif has been modified to bind DNA.

Darwin's question can be refined further, to "how did a serpentine protein gain the ability to respond to light?" Since opsin's light‐sensitivity is mediated by its ability to bind a light‐reactive chemical, called a chromophore, the question can be even further refined to ask how a GPCR must be modified to bind a chromophore.

As a proof of principle, avidin was modified to bind testosterone (Paldanius et al. unpublished results).

To test the possibility of mRNA repair by ExChange, we developed several ExChange (ExCh) molecules AS-E24-AS' based on the efficient TS molecules mentioned above, modified to bind both intron 22 and intron 23 of the dystrophin minigene (Fig. 2A).

In the present study Avd was modified to bind steroid hormones.

The anti-miRNA inhibitors (GenePharma, China) are single-stranded nucleic acids chemically modified to specifically bind to and inhibit endogenous miRNA molecules.

QDs can be activated and deactivated by turning on and off the excitation light, and their surface chemistry can be modified to selectively bind them to specific biological particles to control spatio-temporal resolution in this photostimulation technique.

The current project capitalizes on the innovative synergy of commercially available Fe-NPs (modified to covalently bind to human tissue), and high spatial resolution MRI to enhance visualization of the entire vessel wall ex vivo.

Although based on the similarity with the binding site in humans it is unlikely that emetine can be structurally modified to not bind the mammalian system, as demonstrated in the case of dehydroemetine modifications can reduce its cytotoxicity.

A structural model of human Rac1 from X-ray crystallography [Protein Data Bank (PDB) entry 3TH5], modified to exclude bound nucleotide and magnesium, served as a molecular replacement search model using PHENIX AutoMR.