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We have modified this section slightly for clarity.
We have modified this section of the Results to make the new findings stand out more clearly.
We now completely modified this section and include analysis of amino acid enrichments across the TM for proteins with both extracellular and intracellular N-termini.
We have deleted that statement and modified this section of the Discussion to make clear that we do not know the molecular identity of the neurons and thus the sign of the modulation.
We have dropped the conclusion regarding the "open" conformation and modified this section of the manuscript accordingly (last paragraph of the subsection "In the presence of ATP analogs Mot1 ATPase domain adopts a 'closed' conformation").
We have modified this section and included 2 new figure panels: 1) one that depicts the position of mutations in DCM patients and control populations or from the senior athletes onto a schematic of the TTN meta-transcript 2) a ratio of mutations found in regions C-terminal to the Cronos promoter to those in the N-terminus in different populations.
Similar(54)
I would suggest skipping or modifying this section.
It was not necessary to modify this section as the number of patients who omitted it was low.
The algorithm presented in Fig. 3 is modified in this section in order to ensure termination on any given input.
We thank the reviewer for pointing this out and have modified the section in question ("This failure to reach wild-type activity levels through less improved intermediates, may exist").
We have modified the section on this quantification method to help clarify the issue raised above.
More suggestions(15)
changing this section
modify this section
modified this evolution
modified this view
modified this way
modified this value
modified this position
modified this line
modified this pattern
modified this protocol
modified this procedure
modified this theory
modified this criterion
modified this database
modified this post
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