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Following this conference, a number of major studies have been published that substantially modified the management and course of severe sepsis and septic shock patients.
During the last decade, the introduction of new drugs such as irinotecan (CPT-11) and oxaliplatin (L-OHP) modified the management of metastatic colorectal cancer (CRC).
A possible explanation for this difference is that awareness of parents and investigators as to which vaccines the child had received in the open-label groups modified the management of fever in such settings.
The introduction of new biological molecules, such as etanercept, for the treatment of PsA has modified the management of this disease reaching a good clinical control of the disease [ 8- 10].
Heriot et al. demonstrated that FDG-PET/CT modified the management in 17% of cases with locally advanced primary rectal cancer; MRI with specific contrast agents has proved to be more accurate than ceMDCT and FDG-PET/CT in hepatic lesions <1 cm.
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Site-specific crop management utilizes rapidly evolving information and electronic technologies to modify the management of soils, pests and crops in a site-specific manner as conditions within a field change spatially and temporarily.
In the future, new therapeutic strategies, as oral enzyme administration capable of helping gluten digestion, could modify the management of CD.
In this context, the case-mix adjustment for a complete and standardized set of variables and the knowledge of the outlier status for both assisted vaginal and caesarean deliveries are crucial to properly assess the level of care among institutions, giving the opportunity to modify the management and improve the outcomes [ 4, 37].
Indeed, the identification of mutations in several genes such as NPM1 and FLT3 has revealed prognosis subgroups and modified the clinical management of these leukemias [ 12, 13].
Previous work at Lawrence Livermore National Laboratory LLNLL) has modified the Jemalloc memory management library (Evans, 2006) to enable memory allocation from an address range memory-mapped to a file residing on a storage device.
Our analysis identified two CMOCs that indicate causal pathways between sets of HRM practices and HRM outcomes, and we modified the MRT accordingly: "The management of a well-performing hospital deploys organisational structures that allow decentralisation and self-managed teams and stimulates delegation of decision-making, good flows of information and transparency.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com