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However, Lake Malawi cichlids have modified the developmental program of their cichlid tilapia-like ancestor.
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This study suggests that a reconstitution of nFGFR1 in developing cortical neurons can modify the developmental malformations.
Attenuated associations in preschool-aged children could translate into clinical opportunities for targeted early interventions, aimed at modifying the developmental trajectory of anxiety disorders.
Such mediators alter and regulate homeostasis and may modify the developmental environment.
Environmental stresses could modify the developmental processes when the larvae were exposed to toxicants either in embryonic development or early developmental stages.
Excess atRA does not produce cleft palate through activating AHR, and reciprocally, TCDD does not modify the developmental pattern of atRA signaling in the face.
There are two secondary objectives: 1) to identify environmental exposures that modify the developmental pattern of cytokine responses, and 2) to identify the immunologic correlates of the development of atopic features such as total IgE, allergic sensitization, and atopic dermatitis.
Developmental epigenetic interventions that modified the variance in the gene expression distribution in the hippocampus also modified mouse behavior in tandem [20].
A modular CBT program designed for preteens with ASD, Behavioral Interventions for Anxiety in Children with Autism (BIACA; Wood et al., 2009) was enhanced and modified to address the developmental needs of early adolescents with ASD and clinical anxiety.
These two studies only begin to suggest the power of the early postweaning environment to modify the consequences of exposure to developmental neurotoxicants.
Environmental exposures during this developmental stage modifies the epigenetic programming of the male germline that becomes re-programmed (imprinted-like) and promotes a transgenerational phenotypic variation and adult onset disease state in subsequent generations [ 13– 16].
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