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The presence of H2O and CO2 in the feed-stream was also analyzed indicating that the adsorption of CO2 inhibited the conversion of CO at lower temperatures because these compounds modified the active sites through the formation of carbonaceous species on the catalyst surface.
The neofunctionalization of each new duplicate subtly modified the active site resulting in the specific regioselectivity of oxidation on the indole-like substrate.
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NPI-0052 inhibits proteasome actinhibits covalently modifying the active site threonine residues of the 20S proteasome (Corey activity1999).
Assuming that any of the newly discovered pathways are used at a frequency that is at least 10-fold lower than for the common pathways to WS, it is possible to estimate that only one in one thousand activating mutations would directly modify the active site.
Here, we designed fluorophore or biotin-coupled activity based-probes (ABP) that covalently modify the active center of MALT1.
The post annealing process was employed for modifying the active layer and PEDOT PSS, which was at 140°C for 5 min and at 130°C for 20 min, respectively.
The V67L mutation is proposed to activate splicing by reducing the ensemble distribution of the intein structure and by modifying the active sites.
The most effective TG2 inhibitors to date are small-molecule peptidomimetics featuring electrophilic warheads that irreversibly modify the active site catalytic cysteine (CYS277).
Genetics is used to modify the active site of a single kinase to render it distinct from all naturally occurring kinases.
Here, we provide biochemical evidence that carbamates covalently modify the active site of FAAH by adopting an orientation opposite of that originally predicted from modeling.
High energy mechanical milling (HEMM) was found to effectively improve the reversible capacity associated with the electrochemical kinetics by modifying the active hosts' morphology characteristics.
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