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It uses the modified rules of Particle Swarm Optimization coupled with a carefully designed mutation operator within the framework of cell-like P-systems.
Comparison of the two molecular properties i.e. molecular weight and ClogP, for different families of FDA-approved drugs, suggested that the modified rules of drug-likeness should be adopted for certain target classes [ 13].
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We refer to these values as a modified Rule-of-Five.
In order to apply the modified Rule-of-Five, fragment-based physicochemical descriptors are linearly transformed using the regression analysis presented in Fig. 5.
Due to the number of possible combinations growing exponentially with the number of molecular fragments, a modified Rule-of-Five is applied to exclude those compounds that do not satisfy drug-likeness criteria.
The resulting stiffness of the laminate can be described by a modified rule of mixtures.
The modified rule of mixtures was used to evaluate the efficiency factor.
Equation (5) is analogous to the modified rule of mixtures with a slight difference in the length efficiency factor [12].
Properties of the CNTRC plate are obtained using the modified rule of mixtures approach by introduction of efficiency parameters.
The effective material properties of FG-CNTRC are estimated by the modified rule of mixtures using some efficiency parameters.
A modified rule of mixtures was used to predict the strength of the Cu 24 wt% Ag microcomposites.
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