Exact(6)
The full length CrSPI-1 with this modified role of CrSPI-1-D1 as a thrombin modulator, might play a central role in regulating not only hemostasis but also inflammation, and may provide a close link between these processes and how they might co-evolve in the biological system.
Further, Kl has been found to have a role as an inhibitor in the Insulin and IGF signalling pathway [ 49] (modified role shown in Figure 4).
The exonuclease activity is modulated by mutation of the helicase ATP-binding cleft and by ATP or ADP binding, suggesting a modified role for the helicase domain in the regulation of nuclease activity in these enzymes.
The nuclease activity can be modulated by mutation of the ATP-binding cleft of the helicase domain, and is inhibited by ATP or ADP, suggesting a modified role for the inactive helicase domain in the control of the nuclease activity.
We found out that the dsrC genes in our OMZ SUP05 phages corresponded to one of the two categories described in the Anantharaman et al., category with an incomplete set of conserved residues which suggest a modified role for these genes (beyond sulfur reduction).
Madison Police Chief Mike Koval is reportedly looking to place Kenny in a modified role, possibly on patrol, over concern for the officer's safety following threats made against his life.
Similar(54)
This paper presents RCFTM, a hierarchical agent-based role-changeable fault-tolerant management strategy based on the modified role-changeable management framework for resilient NoC-based manycore systems.
The basic premise behind PSR is that changes in a protein's subcellular location can cause it to take on new or modified roles within the cell.
However unlike Ago2, which is required for siRNA mediated silencing, dFMR1 has been shown to have little to no effect on siRNA efficiency, and is therefore thought to play a stabilizing or modifying role in siRISC function [29], [30], [31].
More recently, constitutive expression of both CB1 and CB2 receptors have been isolated on chondrocytes and implicated in a potential disease modifying role in OA [ 37].
Other studies suggested phenotypic modifying roles for TSC2 and DKK3 [ 21, 22].
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