Sentence examples for modified regulation of from inspiring English sources

It appears that the evolution and occurrence of multiple Hsp70s within a species may be due to modified regulation of Hsp70 substrate-binding activity rather than changes to range of substrate that is recognised [ 28].

TFBS analysis revealed unique TFBSs that exist only in the inserted Bov-A2 elements and thus might represent a classic case of modified regulation of gene expression which may lead to modified function.

It is, therefore, likely that polymorphisms affecting the level or activity of the RelA-associated inhibitor RAI would influence the availability of RelA, and thus modify regulation of apoptosis.

Three of these mention children's unique vulnerability to carbon monoxide, ozone and particulate matter, but do not provide further details, assess additional safety factors or modify regulations in light of this vulnerability.

Previous study has already shown that CR or RSV supplementation modified the regulation of energy balance in mouse lemur [29] but no data was provided about the effects of these treatments on cognitive performances of these animals.

This finding is exciting since recent studies demonstrated that both compound heterozygous brothers of the Hungarian family have reduced TPI mRNA levels compared to their parents and healthy controls [60] suggesting that altered dimer formation resulting in a modified feedback regulation of the TPI enzyme could underlie the pathogenesis of TPI deficiency.

If the ratio of edited products in the cell can be modified by regulation of RNA editing enzymes encoded in the nuclear genome [ 42, 43], then the efficiency of the biological functions involving the edited products can be controlled post-transcriptionally.

The precise functional effects of these changes are unclear, however this use of positively-charged amino acids at sites 488 491 (along with coevolved structural adjustments) could conceivably improve the water hydrogen-bonding network and thus the proton flux from the mitochondrial matrix into the channel, or modify the regulation of proton flow.

Therefore, phosphorylation may modify the regulation of Rho signaling by GDIs, GEFs and GAPs.

Epigenetics allows for adaptive responses of the genome to an ever-changing environment by modifying transcriptional regulation of gene expression.

Therefore, it is likely that the expression level or activity of iASPP would influence the availability of NF- κB, and thus modify the regulation of cell growth.