'modified profoundly' is a correct and usable phrase in written English.
You can use it to describe a situation that has changed significantly, often due to an event or action. For example, "The nation's economy was modified profoundly by the pandemic."
However, though their composition was modified profoundly, with greatly increased representation of white-collar and female employees, they could not keep pace.
Anthrosols are defined as any soils that have been modified profoundly by human activities, including burial, partial removal, cutting and filling, waste disposal, manuring, and irrigated agriculture.
In recent years, our knowledge on estrogen receptors (ER) has been modified profoundly with the identification and the deciphering of the role of its protein effectors, as well as with the deeper insight of its molecular structure/function dynamics, characteristics associated with its nucleo-cytoplasmic-membrane shuttling properties.
The death of John in 1540 and the prompt advance of Austrian forces once more into central Hungary drove Süleyman to modify profoundly the solution that he had imposed in the time of John.
The gut is the silent epicentre of antibiotic resistance, because the antibiotics modify profoundly the gut microbiome, and allow resistant micro-organisms to grow and to colonize this organ for prolonged periods of time [ 9].
All this activity has profoundly modified drama as literature.
In heavily settled regions the makeup of plant and animal life has been profoundly modified.
In the same book, he includes a letter he wrote in 1960 to his German translator, in which he announces that his time in the Lager, and writing about the Lager, "was an important adventure that has profoundly modified me".
Jewish thinkers in Muslim Spain and the Maghrib adopted Aristotelianism (as well as systems that stemmed from but also profoundly modified pure Aristotelian doctrine) considerably later than did their counterparts in the Islamic East.
Opinions may differ widely as to the balance of advantages or disadvantages, from the European and the African point of view, which have resulted from the irruption of the Great Powers of Europe into the African Continent, but no one can doubt that in shaping events that have so profoundly modified recent history Mr Stanley played a considerable part.
The use of these techniques has profoundly modified the transfusion strategy of some clinical teams.
