Sentence examples for modified peptides in from inspiring English sources
Moreover, the presence of NRPS could offer further genetic modifications, which may generate novel genetically modified peptides in the future with high pharmacological importance.
It is recognized, however, that our workflow is unable to pinpoint the acetylation sites or directly measure changes of modified peptides in the acetylated proteins.
However, it provided a global analysis of both unmodified peptides and modified peptides in one run, which could not be achieved with the two previously published ERLIC approaches.
Several trials are currently testing the WT1 235–243 natural sequence and modified sequence [17], [18], [19] in patients who are HLA-A2402; another set of studies tested the WT1 126–134 natural sequence [20] and modified peptides in patients who are HLA-A0201 [21]. HLA-A0201 [21]
For hD1D2, binding was observed to each of these modified peptides in 6 of 6 experiments.
The libraries were incubated with 1 μM for both, unmodified and modified peptides, in blocking solution over night.
Furthermore, the amounts of each modified peptide in the fibers can be varied with concomitant changes in decoration.
For this analysis, we determined the modification sites (positions in the corresponding protein where the modifications occur) for each modified peptide in our results and matched them against the list of known modification sites from Uniprot.
All relative quantifications of the respective non-modified and modified peptides were performed in the positive ion mode with an acceleration voltage of 30 V and scanning range of 300 – 2,000 Da, and were analyzed with MassLynx 4.0 software (Waters).
The broader species distribution of the newly defined putative export system, relative to the NHLP family through which they were detected, provides a unique opportunity to discover additional post-translationally modified peptides families in emerging and existing genomes.
Low-molecular-weight bacteriocins include the lantibiotics and the microcins, which are highly posttranslationally modified peptides that in some ways resemble their nonribosomally synthesized cousins ([ 2] and references therein).
