Sentence examples for modified peptides are from inspiring English sources

This article presents an overview of the expression and regulation of HβD-3 in humans, and the structure function correlations among HβD-3 and its modified peptides are discussed emphasizing the functional importance.

The sequences of modified peptides are shown in Table 1.

Although the unmodified, original sequence of RIAD and smAKAP both demonstrate preferential binding to PKA-RI, the chemically modified peptides are not as inherently flexible and therefore may have altered binding properties including their entropic and enthalpic properties.

The size of the peptides may be an important factor in developing them peptides into potential anticancer drugs, since smaller chemically modified peptides are expected to have increased bioavailability and stability, as well as a reduced immunogenicity.

In this approach, several steps are involved: 1) a prolonged periodate oxidation is performed to convert the O-GlcNAc group to its dialdehyde derivative, 2) hydrazide resin is used to capture the oxidized O-GlcNAc peptides, and 3) after proteolytic digestion, the resulting modified peptides are released by hydroxylamine.

Modified peptides are considered identical to those without modifications should their sequences be the same; and hence are not counted when considering unique peptides.

All relative quantifications of the respective non-modified and modified peptides were performed in the positive ion mode with an acceleration voltage of 30 V and scanning range of 300 – 2,000 Da, and were analyzed with MassLynx 4.0 software (Waters).

Post-translationally modified peptides were filtered by a minimum Mascot Ions Score of 15 and validated by manual inspection.

These rational designs of modified peptides were assayed in term of antimicrobial activity.

Despite the higher levels of H2O2, the modified peptides were not neurotoxic.

The antimicrobial activity of all the modified peptides was also determined so that peptides with both optimal stability and activity could be identified.