Sentence examples for modified peptide has from inspiring English sources

Moreover, the modified peptide has molecular weight 4420.8 g/Mol and has no antigenic regions.

This study suggested that the modified peptide has the promising performance to block the insulin receptor activity that potentially induce diabetes mellitus type 2 in mice.

The results showed that the modified peptide has characteristics 100 h half-life, high-affinity −95.1 ± 20, and high stability 28.17 in complex with the insulin receptor.

Although each of the mentioned post-translationally modified peptides has its importance in Aq-restricted CIA, we have earlier shown that glycosylation of CII is of major importance for T-cell tolerance and pathology in CIA [ 9].

Recently in an effort to increase the affinity of peptides for HLA-B2705 Jones et al. synthesized two modified epitopes with a non-natural arginine analogue at position 2. The modified peptides have decreased ability to bind the HLA-B2705 molecules and were not recognized by CD8+ T cells [33].

We show that altering a few amino acids induced immunogenicity and protectivity against experimental malaria and changed their three-dimensional structure, suggesting a better fit with immune system molecules and that modified peptides having better immunological properties can be included in the design of new malaria multi-component subunit-based vaccine.

Similar to unmodified peptides, incorrect peptide spectrum matches (PSMs) of modified peptides have an equal chance of being derived from either the target or decoy database.

The frequency of peptides for each group size, shown in Supplementary Figure S1, exhibits a heavy-tail distribution where the majority of modified peptides have low counts.

The H3K9me3 and H3K36me3 modified peptides had similar kcat values (kcat = 0.145 s−1 and 0.166 s−1, respectively), but H3K9me3 manifested the highest k cat/K m (0.004393 s−1.μM−1 for H3K9me3 and 0.001161 s−1.μM−1 for H3K36me3), consistent with previous reports.

In this way, SPOT arrays containing hundreds of modified peptides have been used to profile the specificity of a range of sequence specific methyllysine reader domains, including the CDs of HP1β and HP1γ, the PHD finger of the chromatin remodeler ATRX, and the PWWP domain of a DNA methyltransferase, among others.

When nornicotine, glucose and peptide were incubated together, the result was a modified peptide that had little tendency to agglomerate.