We show, through transmission experiments in transgenic mice expressing porcine prion protein (PrP), that the susceptibility of this mouse model to bovine spongiform encephalopathy (BSE) can be enhanced after its passage in ARQ sheep, indicating that the pathogenicity of the BSE agent is modified after passage in sheep.
OBJECTIVE: Although numerous diseases involving cellular proliferation are also associated with phenotypic changes, there has been little direct evidence that cell phenotype and the cell's response to external stimuli are modified during passage through different phases of the cell cycle.
It is possible that histones in the ORG and εγ domain regions are modified by passage of the RNAPII complex as part of decondensation of the globin locus, but that active marks in these regions are rapidly or more thoroughly turned over due to the rarity and very low level at which these transcripts occur.
The focusing ability is based upon constructive interference of the X-ray wavefront, modified by passage through the zone plate, either in phase or more commonly by attenuation due to the zones.
It consists of fifteen songs punctuated by monologues, many of which are modified from passages in "Born to Run".
The level of expression of multidrug resistance 1 (MDR-associatedociated protein 1 (MRP1) and, breast cancer resistance protein, three members of the ATP-binding cassette transporter family was not modified over passages.
The Hebrew texts in particular feature what have been called "key-words," words or phrases repeated and subtly modified in a passage, as a kind of threaded meaning.
Although Christianity was introduced by missionaries after 1910, traditional animism and religious rites of passage, modified somewhat by earlier Hindu influence, continue to be important.
Also, the more rapidly filtration occurs, the less time there is for the urine to be modified during its passage through the tubules.
Most Jews based their faith and practice on the five books of Moses (slightly modified by the passage of time) and rejected the extreme positions of the three parties.
We have emphasized that we used microtubule recruitment for diagnostic purposes, and modified the highlighted passage.
