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"These bugs have been right under our noses for so long, and no one has noticed that their helmet is a highly modified pair of wings," says Jim Marden, an evolutionary biologist at Pennsylvania State University, University Park.
As shown in Table 2, the pairs with the wild-type cleavage domains and the DDD/RRR pair gave very good yields of mutants, whereas the singly modified pair, DD/RR, was dramatically less effective.
Each of these is a modified pair of ancestral limbs.
Another of the Silurian millipedes has a paired structure on the anterior part of the trunk, in the usual segmental position and with a characteristic form of a gonopod, a modified pair of legs that male millipedes use to transfer sperm to the female's genital opening (Fig. 3; Wilson and Anderson 2004).
Maxillipeds, a modified pair of appendages, also serve as accessory mouthparts.
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In the current study, we used a modified paired repetition suppression design with 9-month-old infants to identify which cortical regions are suppressed when the infant observes a repeated goal versus a new goal.
Four modified pairs of primers, designed to amplify the converted DNA, were designed using the MethPrimer software [37] (Table 2).
After normalization, the Bioconductor [22] Significance Analysis of Microarrays package [23] was used to compute modified paired t-tests that contrasted an affected twin with the unaffected co-twin for each transcript using R [24].
Genome libraries were prepared using a modified paired-end tag (PET) protocol supplied by Illumina Inc.
The WGSS library was prepared using a modified paired-end protocol supplied by Illumina Inc. (USA).
The whole genome shotgun sequencing library was prepared using a modified paired-end protocol supplied by Illumina.
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