Sentence examples for modified murine model from inspiring English sources

This model was the very first line of genetically modified murine model for atherosclerosis studies introduced to the research community.

The present experiments demonstrate, for the first time, an atrial arrhythmic and conduction phenotype in a genetically modified murine model deficient in the β3 subunit of the Na+ channel.

Nevertheless, these findings in the present study demonstrating alterations in the transmural repolarization gradient are in agreement with recent findings describing alterations in apico-basal repolarization patterns in a genetically modified murine model of human LQT3 syndrome (Tian et al. 2007).

Bone marrow transplantation experiments in genetically modified murine models have been a powerful tool to examine whether immune cells contribute to a given pathology in vivo.

Atherosclerotic lesions have also been observed in genetically modified murine models, that is, LDLR−/− and apoE−/− mice after chronic consumption of an oxidized cholesterol diet [ 129].

Genetically modified murine models are powerful tools for studying the pathophysiological mechanisms of human diseases, and are now increasingly used to study the complex interactions between the gut microbiota and host in normal homeostasis and disease.

Mammary tumors from other genetically modified murine models (FVB/N) were generously provided by Drs. Kim and Alexander (University of Wisconsin) (MMTV-neu [ 28], and Drs. Green and Zi-Yao Liu (NIH-NCI) (C3(1)-SV40 Tag tumors [ 29].

We compared levels of transcripts in the ERα-associated "luminal" signature that defines this subtype of tumors in women and transcripts enriched in various mammary epithelial lineages to other well-studied genetically modified murine models of breast cancer.

The availability of different genetically modified murine models with potentially interesting bone phenotypes increased also the demand for noninvasive methods to effectively compare their differences during growth and development.

Researchers have used genetic technology to produce a number of genetically modified murine models to overcome the many deficiencies of larger animals, particularly to allow studies of potential therapies that require large numbers of subjects.

To compare the phenotype of NRL-PRL tumors more closely to other well-studied genetically modified murine models of breast cancer subtypes in the FVB/N strain background, we compared levels of transcripts for ERα-associated genes in the "luminal" signature [ 20] and those enriched in various mammary epithelial lineages.