Sentence examples for modified mouse strains from inspiring English sources

Based on shared markers between astrocytes and stem cells, we discuss genetically modified mouse strains with overlapping expression, and highlight SOX-expressing strains available for targeting of stem and progenitor cell populations.

This chapter aims to (i) provide a current overview of selected mouse databases and online information resources of relevance to transgenic and gene targeting research and (ii) highlight and promote the use of standardized nomenclature for naming transgenes, targeted and gene trap mutations, and genetically modified mouse strains and embryonic stem cell lines.

Genetically modified mouse strains derived from embryonic stem (ES) cells have become essential tools for functional genomics and biomedical research.

The generation of genetically modified mouse strains by homologous recombination in embryonic stem (ES) cells is a major research tool in diverse fields of biology.

The kinetics in both genetically modified mouse strains were almost identical suggesting that the majority of these changes were accounted for by a lack of TXA2 production by the host in COX-1 null mice.

There are genetically modified mouse strains available for each PPAR.

As a prelude to experiments in humans, we used genetically modified mouse strain HHD, which expresses as the only MHC class I molecule chimaeric human (α-1 and α-2) and mouse (α-3) HLA-A*0201 HLA-A*0201n covalently linked to theavyman β2m light chain.

Wedemeyer et al. recently evaluated a genetically modified mouse strain with alpha-CGRP-gene deficiency in order to gain a better understanding of the alpha-CGRP-mediated effect in particle-induced osteolysis.

We analysed data, derived from a RNA-seq experiment including RNA samples, extracted from amygdalae micro-punches of a genetically modified mouse strain (Brd1+/−) and of their wild-type (WT) littermates (8 biological replicates/group), with Cuffdiff2, edgeR, DESeq2 and TSPM.

The motivation for the transfer to this strain is the prospect of genetically modified mouse studies, which are most often on a C57BL/6 background.

We routinely use 6 20 week-old C57BL/6 mice, but we have also successfully used mice from other strains (129S1/SvImJ, BALB/c and CD1) as well as several genetically modified mouse models.