Sentence examples for modified mice show from inspiring English sources

These genetically modified mice show changes in gene expression in particular brain regions and altered behavior.

Studies using genetically modified mice show that RORα and REV-ERBα play a role in maintaining circadian rhythm.

A series of elegant studies in genetically modified mice show that sweet and umami tastes are dependent on T1R-receptors, that bitter taste is caused by stimulation of T2R receptors, that these two receptors never are found in the same taste receptor cell (TRC) and that the TRC determines the behavioral response [ 1- 7].

In fact, all the adult tissues of the genetically modified mice showed only EDA+ FN mRNA, demonstrating the fidelity of in vitro models, despite of the development- and aging-regulated splicing regulation of the EDA exon, and regardless of the presence of exonic elements described within the exon.

This hypothesis is further supported by experiments in genetically modified mice showing that compound heterozygous mice carrying one cardiomyopathy-associated mutation and one null mutation in Lmna have a more severe phenotype than homozygous mice with two cardiomyopathy-associated mutations.

The importance of the fibrinolytic system in sepsis also has been demonstrated in genetically modified mice, showing that endotoxin-induced fibrin deposition in organs of mice deficient for tPA or uPA was more extensive than that in wild-type mice, and the opposite held true for PAI-1-deficient mice [ 22].

Recently, mouse haploid embryonic stem cells (haESCs) have been successfully derived from parthenogenetic (PG) and androgenetic (AG) blastocysts, and applied to forward or reverse genetic screening and production of genetically modified mice, showing a great potential in genetic studies in mammalian organisms.

Therefore, it is of interest to test whether these genetically modified mice would show the quantitative and qualitative differences in adult male songs we observed.

Using tissue from genetically modified mice, we show that the dilator effects of GW0742 are independent of the target receptor PPARβ/δ or cell surface prostacyclin (IP) receptors.

Interestingly, the genetically modified mice still showed the classic male-mating repertoire mounting, penetration and ejaculation.

The phenotype in Fsp27−/− WAT is reminiscent of that of FoxC2 overexpression transgenic mice [22] and p107 and Rb knockout mice [23], where PGC1α and Ucp1 are upregulated and that WAT of these genetically modified mice all showed brown adipocyte-like metabolic activity.