Sentence examples for modified mice for from inspiring English sources

One of the major limitations in the use of genetically modified mice for studying cognitive functions is the lack of regional and temporal control of gene function.

This study emphasizes the importance of mouse strain selections in the production of genetically modified mice for investigating phenotypes and mechanisms of psychostimulants.

In inherited neurodegenerative disorders the engineering of genetically modified mice for the causative genes have provided new insights in the understanding of axono glial interactions.

The findings that genetically modified mice for IF successfully mimic certain degenerative neuropathological phenotype [81].

One of the motivations behind FASTER is to increase the throughput of sleep staging, for example, to screen a large number of genetically modified mice for defects in sleep.

The aim of this study was to investigate the importance of total estrogen receptor alpha (ERα) expression and cartilage-specific ERα expression in genetically modified mice for the ameliorating effect of estrogen treatment in experimental arthritis.

Recently developed synthetic ligands and genetically modified mice models for PPAR-β/δ have increased our knowledge of its role in metabolism, inflammation, and angiogenesis.

Interestingly, most of the genetically modified mice available for the study of breast cancer do not express ER and PR [ 2], leaving few models available in which to address hormone-dependent tumor progression specifically.

Genetically modified mice provide models for Alport syndrome evolving to renal failure that have resulted in clinical recommendations, polycystic kidney disease models that have provided clues for the development of tolvaptan, that was recently approved for the human disease in Japan; and animal models also contributed to target C5 with eculizumab in hemolytic uremic syndrome.

These genetically modified mice are tested for how they differ from ordinary mice in their response to toxic chemicals.

As such, the capacity for generating genetically modified mice is often limiting, even for the most well-funded laboratories.