Sentence examples for modified messenger from inspiring English sources

Li, B., Luo, X. & Dong, Y. Effects of chemically modified messenger RNA on protein expression.

Dr. Kugler showed me his modified messenger bag in which he carries his instruments.

Modified messenger RNA (mRNA) has recently become a new prospective class of drug product.

We demonstrated in vitro that transfection with ACE2 chemically modified messenger RNA (cmRNA) leads to robust translation of fully matured, membrane-anchored ACE2 protein.

Transcript therapies using chemically modified messenger RNAs (cmRNAs) are emerging as safe and promising alternatives for gene and recombinant protein therapies.

Therefore, we propose a systemic delivery of chemically modified messenger RNA (mRNA) as an alternative to plasmid DNA (pDNA) in cancer gene therapy.

Finally, fatty acids could modify messenger ribonucleic acid stability, as stated before, and also alter de novo synthesis of the transcription factor, altering protein synthesis.

Upstream and 5′-UTR variants can disrupt epigenetic regulation and transcription factor-binding sites, 3′-UTR variants can modify messenger RNA stability (Boffa et al. 2008), intronic SNPs can influence expression breadth (Park et al. 2012), and synonymous SNPs can affect translation efficiency (Plotkin and Kudla 2011).

The scientists then modified some messenger RNA by lopping off its chemical cap and left the rest intact so that when they reconstituted the machine in test tubes, they could compare the behaviors of capped and uncapped versions of messenger RNA.

Splicing of the modified pre-messenger RNA's in vitro revealed that, although a 2'-hydroxyl is not absolutely required at either splice site, the 2'-hydroxyl at the 3' splice site is important for the second step of splicing.

ORs have also been proposed to initiate, or be modified by, second messenger cascades.