Sentence examples for modified mRNA levels from inspiring English sources

Contrary to 6 month old female mutant mice, 24 month old female mutant mice had more genes with modified mRNA levels than did the male mutant mice of the same age group (22 vs. 10).

At 6 month of age, male and female mutant mice had 15 and 4 genes with modified mRNA levels, respectively; however, at 24 month of age, there were 10 and 24 genes with change expression levels in male and female mice, respectively.

Leptin given by gavage did not significantly modify mRNA levels of these enzymes.

Hypoxia seemed to significantly modify mRNA levels of CD49d in BM-MSCs and CD44 in AT-MSCs, which is in agreement with other studies that have described different expression profiles for CD49d[ 45] and CD44[ 46] in hypoxia.

We have previously shown that the brain gene expression profile of domestic dogs has diverged from that observed in their wild ancestor the gray wolf, suggesting that behavioral selection during domestication has modified mRNA expression levels of genes with multiple functions [ 4].

MicroRNA (miRNA -related single nucleotide polymiRNA -relatedsingle compromise miRnucleotide affinity and modify mRNA expolymorphismslSNPs the target genes, thus leading to cancer susceptibility.

Human tRNAse ZL was found to bind half-tRNA fragments in the cytosol, and it is now known that such complexes are capable of modifying mRNA expression levels, including those of genes involved in p53 and apoptosis.

Fig. 1 The principle and applications of modified mRNA.

This modified mRNA is then translated into proteins.

For the synthesis of modified mRNA, mRNA synthesis was performed as reported previously.

A graphical view and clusterization analysis revealed that intact EVs elicit a response in host cells that is more marked at 6 hrs after treatment, is maintained after 24 hrs, but decays towards 72 hrs, where most cellular modified mRNAs returned to basal levels.