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The first of these is modulation of half-life via modified interaction of the Fc with the recycling receptor FcRn (Roopenian and Akilesh, 2007; Baker et al., 2009).
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A detailed energetic and structural knowledge of these interactions is necessary to understand the complex regulatory and metabolic interaction networks that occur in living organisms, with the ultimate goal of designing drugs for blocking or modifying interactions of therapeutic interest.
Acidification of samples to a pH of 3.5 modified interactions between IL-13 and its receptor so that epitopes recognized by assay antibodies were set free for binding to capture and detection antibodies.
In this paper we examine expression of cell adhesion molecules on neuroblastoma to determine which of these modify interaction with NK and LAK cells.
Two sulfotransferases that can modify the extent of proteoglycan sulfation were also differentially regulated, and may modify the interaction of a subset of proteoglycans with their binding partners during cerebellar development.
Gallium also modifies the interaction of MoS2 with the support, decreasing the numbers of Mo O Al anchors and increasing the stacking of the MoS2 slabs.
This work analyzes how a modification in the original design of the diffuser currently in use in a Cuban power plant, already studied in the first part of this investigation and consisting in the addition of a finned swirler ring, modifies the interaction of the air stream with the liquid spray.
At this frequency and regardless of pressure, the flame motion is driven by flame vortex roll-up, suggesting that pressure affects the FTF by modifying the interaction of the flame with the vortex detached from the injector rim during a forcing period.
Extensive post-translational modifications (glycosylation, phosphorylation) can modify the interaction of OPN with other proteins.
Specific adaptor proteins are known to modify the interaction of substrates with ATP-dependent proteases (reviewed in [6] [8]).
It will be interesting to examine if such ligands can modify the interaction of FKBP52 with APP and Aβ.
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