Sentence examples for modified in the course of from inspiring English sources

The common-law system was extensively modified in the course of the 20th century.

We rather started with certain expectations that we eventually modified in the course of our investigation.

This formulation involves a variable ground structure for topology optimization, since the shape of the shell is modified in the course of the process.

Inquire first, whether species have a real and permanent existence in nature; or whether they are capable, as some naturalists pretend, of being indefinitely modified in the course of a long series of generations (1832).

The morphogenesis of polar structures such as root-hair bearing cells of Lactuca primary root has been shown to be modified in the course of differentiation under mass acceleration diminished below 0.1 g.

Therefore, the value and direction of the loading are coupled to the shape of the structure and they change as the material layout of the structure is modified in the course of the optimization process.

This basic plan has become so modified during the course of evolution that in some forms it is difficult to recognize.

These were modified during the course of the study in line with comments received from staff and to comply with the revised DH RA tool introduced in March 2010.

Furthermore, we wrote item-specific instructions, which we found very helpful and likely increased the agreement for most items, except for the two items whose instructions were modified during the course of the quality assessment (in some cases between the first and second rating for individual studies).

HSCT has been successful in modifying the course of the disease in patients with severe MPS I and MPS VI.

This proof-of-concept and dose-ranging study failed to demonstrate efficacy of PG-116800, an MMP inhibitor, in modifying the course of knee OA in patients with mild to moderate disease during a 12-month treatment period, as determined by microfocal x-ray assessment of JSW and analysis of WOMAC total scores, despite promising results of nonclinical studies [ 9, 10, 12].