Sentence examples for modified in cells from inspiring English sources
Next we sought to know whether OGT itself is O-GlcNAc modified in cells transfected with tyrosine PHB mutants.
We have previously shown that the content and the activity of the catalytic subunit of PP2A (PP2Ac) is modified in cells with altered Arl2 content [20].
These findings, coupled with the work presented here shed new light on how SIRT1 can be modified in cells by postranslational modifications and in particular how SIRT1 can differentially respond to physiological events, like oxidative stress.
Based on the fact that vesicle protein composition was barely affected by mutations in SEC4, SEC1, BOS1, VPS23, and SNF7 genes, we evaluated whether the relative abundance of vesicle proteins would be modified in cells bearing defects in expression of the related proteins.
Our data support that Pin1 is covalently modified in cells primarily at the catalytic cysteine upon generation of HNE.
According to their regulatory states, three different sets of genes can be identified: C1-genes are associated with nucleosomes that are stably modified in cells residing in the niche.
We have previously shown that Hsp27 functional inhibition, by interfering peptides called aptamers, could modify the in vivo proliferation of tumours, whereas proliferation was not modified in cell culture conditions (Gibert et al, 2011).
Interestingly, expression level of the PRC1 member Bmi1 is not modified in senescent cells as compared to young proliferating cells (Fig. 1C) [1C].
Since senescence pathways are modified in immortalized cells [ 21, 22] we conducted in vivo experiments to test whether Ku86 protects normal cells from high NaCl-induced cellular senescence.
In this review we discuss microRNA genes that are epigenetically modified in cancer cells, and the role that microRNAs themselves can have as chromatin modifiers.
The effect of electromagnetic radiation on biological objects extends from heating to complex photochemistry, and includes DNA alteration, that properly modified in damaged cells may entail beneficial effects.
