Sentence examples for modified histones have from inspiring English sources

Six different modified histones have been chosen as the focus of a large amount of research due to their association with specific gene structures.

In the last 10 years, methods to produce site-specifically modified histones have burgeoned.

Asymmetrically modified histones have also shed light on the mechanism of PTM binding and crosstalk.

Modified histones have been poorly studied in woody tissues, despite their importance in growth and development.

Modified histones have contributed immensely to biochemical and biophysical analyses in vitro.

We found a trend that further supported this hypothesis: the expression levels of genes associated with broad promoters that had modified histones had higher expression levels than genes associated with broad promoters without modified histones.

Complex models for the deposition and turnover of nucleosomes with particular modified histone compositions have been proposed that preserve their position in chromatin, a process known as chromatin domain inheritance (CDI).

To investigate the upregulation of genes associated with histone acetylation and their dependence on promoter type, we made two groups of histones: one having modified histones (18 types of acetylated histone) around TSSs (from -500 bp to 500 bp) and the other having no modified histones.

However, the expression and prognostic significance of modified histones in breast cancer has not been previously explored.

The second agent, arginine butyrate has the potential for beneficial effects via two routes, it makes arginine available as a substrate for nNOS, while the butyrate moiety modifies histones and has widespread effects on gene expression.

Therefore, for histone methylation, we made the following two groups, one having H3K4me1, -2 or -3, which are known to upregulate downstream genes, and the other having no modified histones.