Sentence examples for modified gene sequences from inspiring English sources

A distinction needs to be made at this point to indicate that the issue raised here is not an argument against patenting of inventions based on "modified" gene sequences; it is the practice that enables the isolated, but otherwise unmodified, genomic DNA to be included in patent claims that is being questioned.

There were F. graminearum 69 entries, including 59 putative transcription factors [ 48] and 8 kinases [ 49], an ATP citrate lyase ACL1 [ 50] and a syntaxin-like SNARE gene GzSYN1 [ 51] from PHI-base that had modified gene sequences in the RRes v4.0 gene set versus MIPS v3.2 (see Additional file 11).

This strategy opens a venue for functional gene dissection experiments where modified gene sequences can be tested for their ability to encode functional protein that can complement the RNAi-based loss-of-function phenotype.

In addition, we cloned complete cDNA of IFS [GenBank: JN828952] and I3'H [GenBank: JQ609280], and modified gene sequence to increase protein solubility for successful expression and characterization (unpublished data).

The company uses the well-established polymerase chain reaction method to search for the telltale gene sequence of a modified gene.

This modified helper phage encodes a modified gene III, encoding a peptide sequence which will be cleaved by trypsin, between domain D2 and D3.

The modified gene was ligated into pGEM-T Easy and verified by sequencing.

Furthermore, DHCBP significantly modified gene expression.

The modified lysostaphin gene only contains the functional genes but not signal genes (see Table 2 about the modified lysostaphin gene sequence), and the modified lysostaphin gene was inserted into the pQE30 vector using conventional cloning techniques, with restriction enzymes BamHI and HindIII.

Here, we used the retroviral mRNA delivery approach to study the impact of modifying gene-flanking sequences on RNA transfer.

Our findings highlight the notion that morphological changes rather occur by modifying gene regulation than sequence (see [60]) and open interesting and new perspectives in the field of the study of lamprey regulatory sequences and comparative genomics.