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339 (35%) of modified gene models showed a net increase in total exons while 126 (13%) showed a net decrease.
For the 974 significantly modified gene models, it is useful to look more closely at the nature of the modifications made.
Of the 974 modified gene models, 453 (30%) had no error flags within their FDM sequences, but showed a more that 10% increase in gene size.
Of the set of 1501 gene models, 1439 (96%) generated modified gene models from BES's in which all error flags were successfully spanned and sequences aligned to genomic sequence.
A vast majority of the Myc-BestModel gene models (1439 or 96%) generated modified gene models with all error flags were successfully spanned and transcript sequences well aligned to genomic sequence.
Of the set of 1501 gene models, 1439 (96%) successfully generated modified gene models in which all error flags were successfully resolved and the sequences aligned to the genomic sequence.
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The modified gene model file was added to the bitbucket repository subdirectory titled BlastxAnalysis/results as V_corymbosum_scaffold_May_2013_wDescr.bed.gz.gz
At any phase, curators could add or modify gene models.
Web Apollo [ 32] annotation tools allow registered BeeBase users to modify gene models, and can be used to manually correct split or merged genes [ 33].
"Tell us the gene you want modified and we will give you the modified gene with the full analysis," Dabrowski said.
Genome editing tools such as the clustered regularly interspaced short palindromic repeat (CRISPR -associated system (CRISPR -associatedely usystem modify genes in model systems inCasding animal zygotes and haven cells, and hold tremendous promise for been basic research and clinical applications.
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