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The instrument was further modified following a pilot study of 80 abstracts that were scored by two raters and subsequently discussed in detail.
Transcriptomic analysis has emerged as a powerful tool to decipher cellular pathways that are modified following a gene expression alteration as it does not pre-require the need of restricting hypothesis.
The questionnaire was modified following a small pilot study, leading to changes in the format of the questionnaire and minor alterations in the wording of questions, before being distributed by post to the research population.
Additionally, the above-mentioned model was modified following a suggestion by Shipley and Meziane (2002) to test for non-linear allometric allocation in LAR and RSR as a function of plant size.
16 17 This was approved by the funder and by the local ethics committee on the understanding that the design of the study could be modified following a consultation/modelling phase which would involve focus groups of patients and carers and one-to-one interviews with a range of HCPs about the proposed trial design.
In the prsent study, we have successfully used gene expression profiling in whole blood to establish genes that are differentially regulated between patients with CAD and control subjects, and whose expression is modified following a cardiac rehabilitation programme in patients with CAD.
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The person answering the hotline was a parent or a midwife, trained according to fixed algorithms that were prepared and modified following findings from a previously published pilot hotline study [ 14].
The circuit was heavily modified following the race, including a change at Tamburello also the scene of major accidents for Gerhard Berger (1989) and Nelson Piquet (1987)—from a high speed corner to a much slower chicane.
'Node' refers to placement on phylogeny in Additional file 3. Fossil ages follow the references, except that some ages are modified following [ 49], indicated with an asterisk.
Questionnaires were modified following that feedback.
They were modified following pilot application on two wards.
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