Sentence examples for modified cells were from inspiring English sources
The researchers showed that long-term grafting was only possible if the genetically modified cells were holoclones — a relatively rare type of immortal cell that can self-renew indefinitely.
These modified cells were grown into early embryos, or blastocysts, which were clones of the afflicted mice.
Ten billion modified cells were then reinfused into the participants' bodies, and the new data show that about 25% of cells had the mutant CCR5s.
She notes that the study is also a huge logistical achievement because ALD is so rare, the trial took place at seven sites in five countries, where each patient's genetically modified cells were carefully shipped from a central manufacturing site.
For comparison, Kupcsik et al. (Kupcsik et al. 2010) reported that sox9 gene transfer in isolated human bone marrow-derived MSCs enhanced the production of matrix components under mechanical stimulation but not when modified cells were maintained in static culture conditions.
First, the organisation of the root cap was strongly modified: cells were smaller, aberrant division planes could be observed and the distribution of amyloplasts in the columella cells was altered (data not shown).
When one of these genetically modified cells is hit with yellow light, the pump brings a negative charge into it, preventing it from firing.
Selection of genetically modified cells is a critical step to engineer the cells with desired properties.
To overcome this problem, a positive screening method for genetically modified cells is proposed using a pair of chimeric receptors that trigger a growth signal in response to a specific antigen.
If they do, those modified cells are implanted into a mouse embryo and then into a surrogate mother mouse, who, hopefully, gives birth to mice that have been successfully modified.
The pattern of contribution by genetically modified cells is distinct between the early and late phase post transplantation and emphasizes the importance of long-term studies to assess the risk of integrating vectors.
