Sentence examples for modified cell population from inspiring English sources
Efficient selection of the genetically modified cell population is a critical step to obtain the cells with desired properties.
Because these hapten dimers are not harmful for normal cells, the approach will be especially useful for reversible in vitro or in vivo expansion of genetically modified cell population employed for cell therapy and tissue engineering.
The gene-modified cell population can be viewed as a genetic mosaic whose complexity depends upon the target cell type, the number of transduced cells, the average number of insertions per cell, the genetic stability and composition of the transgene, and the integration pattern of the vector.
Using genetically modified cell lines, the 'claudin-low' population expressed low levels of Claudin 3 and E-cadherin and also expressed EMT markers such as vimentin and Twist, suggesting that claudin-low cells may have derived from immature progenitor or stem cells [ 70].
The proportion of basal cells increased in Wnt1-induced hyperplastic populations, as observed before using a modified cell separation protocol (Fig. S2 [10]).
The project began as a modified cell phone but is now available as an iPhone app.
Autologous T cells can be transduced and immediately selected in vitro using a marker gene included in the vector, so that the reinfused population contains a high percentage of genetically modified cells.
Populations containing multiple species are important in natural ecosystems, well-defined processes, wastewater treatment, and systems using genetically modified cells.
Genetically modified cells may require special conditions.
A more realistic aim for stem cell therapy to restore injuries to the CNS might be the implantation of genetically modified stem cell populations in order to produce neurotrophic factors (like BDNF, NT3 or GDNF), with the potential to enhance survival of existing neurons and endogenous neuroregeneration [ 6, 7].
The absence of genotoxicity is determined by the lack of growth of the genetically modified T-cell population upon removal of the AaPCs and cytokines, as well as by demonstrating a normal karyotype.
