Sentence examples for modified by polymorphisms from inspiring English sources

These were cloned into an expression construct lacking a vector-based promoter, so that β2AR expression was driven by its promoter, and steady state expression could be modified by polymorphisms throughout ADRB2 within a haplotype.

Interestingly, the abundance of a transcript is directly modified by polymorphisms in regulatory elements [ 161].

Nor did we find this association to be modified by polymorphisms in the ALAD gene or by medication use.

Future work could study if the effect of PM on preterm birth is modified by polymorphisms in proinflammatory cytokine genes.

A potential effect of methyl donor intake on DNA methylation may be modified by polymorphisms in folate metabolizing enzymes.

Case control studies suggest an association between blood lead and essential tremor, and that this association is modified by polymorphisms in the δ-aminolevulinic acid dehydrogenase (ALAD) gene.

An eQTL approach investigates how the abundance of a gene transcript is directly modified by polymorphism in regulatory elements.

Exposure to traffic-related air pollutants was associated with an increased risk of sensitization at four years in children with specific variants of GSTP1 and this association was modified by polymorphism in genes encoding TNF.

Another paper evaluated whether potential effects of traffic-related pollutants on doctor-diagnosed asthma, wheezing symptoms and sensitization were modified by polymorphism in genes encoding glutathione S-transferase P1 (GSTP1) and tumour necrosis factor (TNF) [ 28].

Because the cellular signaling of TLRs can be modified by polymorphism [ 4] and the subunits of NF-kB expression may be affected by DAA [ 5], participants in DAA clinical trials should have TLRs and NF-kB expressions as similar as possible so that groups can be appropriately compared.

Therefore it is possible that the effects of increased expression of MYLK in AA astrocytes may be further modified by genetic polymorphisms.