Sentence examples for modified by phosphorylation from inspiring English sources

In two designs, Erbin's peptide binding function is modified by phosphorylation, where the presence of the phosphate group destabilizes peptide binding.

Comparing the five successful designs to the unsuccessful cases, we find a trade-off between protein stability and the ability to be modified by phosphorylation.

In this study, we show that in cells committed to die, a portion of the cellular DEK pool is extensively posttranslationally modified by phosphorylation and poly(ADP-ribosyl)ation.

Some compounds may have multiple states, for example, a protein may be modified by phosphorylation.

When Y217 is replaced by F or modified by phosphorylation, the hydrogen bond is disrupted.

Treating the cell lysate with λ phosphatase elimnated the multiple upper bands, suggesting that Atg31 is modified by phosphorylation (Fig. 1B).

The 421 mouse monoclonal antibody has also a low affinity for p53 mostly, because its epitope can be heavily modified by phosphorylations, ubiquitinylation, acetylation, methylation and neddylation.

We have previously observed that WRN catalytic activities are severely modified by its phosphorylation status [27], [28].

EHEC and EPEC Tir C-termini appear to be modified by serine/threonine phosphorylation upon entry into the host cell [19], [20].

Notably, heterozygosity for the targeted β -catenin E654 allele predisposed to intestinal tumours confirming the tumour-promoting potential of β-catenin modified by Y654 phosphorylation.

For example, CtBP activity is modified by HIPK2 phosphorylation (Zhang et al, 2003), and HDACs such as Rpd3 have also been shown to be phosphorylated by MAPK in response to cellular stress (De Nadal et al, 2004).