Zittrain's outlook is cynical but wise; he goes into great detail about the ways in which "tethered technology" (iPhones, Kindles, G.P.S. devices, Facebook accounts) can easily be controlled and modified by the few for the many, with minor repercussions.
However, following gene duplication, the binding properties of an OR gene (or any receptor) may be modified by a few changes to the binding site.
This model could be modified by mixing only a few transformed keratinocytes with normal keratinocytes in varying ratios to determine if similar results are observed or if there is a suppressive effect of the normal keratinocytes.
There is a suggestion that the association of CRP with CVD is modified by diabetes status (8); however, few such studies exist.
In mouse and human embryonic stem cells, a large number of PRC2 targets were covered by bivalent domains with H3K4me3 and H3K27me3, but few were modified by H3K36me3 [ 22, 23].
Previously, DHA has been reported to react with the imidazole group of His and the ε-amine group of Lys (Kanayama et al., 1987); however, we did not detect His modification and only detected a few sites modified by Lys, which could reflect the relatively low level of free His and Lys in the lens.
This was only true for the FTF item "difficulty getting started on a task/activity", however, the conclusion should be modified by the fact that very few children (n = 7) were rated with a "certainly true" report on the "appears to be slow, sluggish or lacking energy" item.
Although noise levels could be readily modified by applying some simple strategies [23], few of those responding to our survey used methods to reduce noise or to assess how noise affects patient comfort.
The data suggests that the IRF2 IRES is highly structured as very few nucleotides were modified by DMS.
Mr. Augustin and other founders of the company, and the movement, contend that by making computer code underlying a program freely available, and readily modified by anyone, a stronger system with fewer crashes results, ending the domination of operating systems owned by one company, especially Microsoft Windows.
