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Since the APACHE III was originally designed for use in intensive care unit (ICU) patients, the score has been modified by excluding variables that are not applicable to this study population [21], [24], [25].
In addition, these criteria have also been modified by excluding the PatGA.
These findings were not modified by excluding individuals carrying the S/S genotype of the serotonin transporter gene-linked polymorphic region.
In order to analyze T2DM only the algorithm was slightly modified by excluding the code E10, which codes type 1 diabetes.
Asthma was defined according to GINA (Global Initiative for Asthma) guidelines which were modified by excluding the symptom of "chest tightness", spirometry/peak expiratory flow measurements and by adding chest x-ray findings to distinguish asthma from pneumonia.
Since the APACHE III was designed for use among intensive care unit (ICU) patients, the score has been modified by excluding variables that are not applicable to this study population [ 12- 17].
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The original Larsen score [ 10] was modified slightly by excluding grade 1 [ 11], so that the scale became 0 to 4, as described previously [ 6].
The data obtained for specific investigation were refitted with a modified model obtained by excluding the non-significant variables from the general predictive equation and the results of statistical analysis obtained for the sequence of experimentations are summarized in Table 3.
Since this study included participants who many not have been in an ICU at the time of bacteremia, we modified the score by excluding variables that were not applicable to our study population (i.e. pulmonary arterial gradient, urine output, neurologic status and ventilator data) as has been done in other studies [ 20- 24] 24].
We then compute for the CRT by following the same approach as specified by Balint et al. (2011); however, we modify this approach by excluding vegetation from the equation since in this case, vegetation will be the dependent variable leading to the functional form in Eq. 3: {mathrm{CRT}}_{i,m}={W}_{mathrm{RVI}}ast {mathrm{RVI}}_{i,m}+{W}_{mathrm{TVI}}ast {mathrm{TVI}}_{i,m} (3).
We used a modified version of this by excluding liver disease.
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