Sentence examples for modified by cell from inspiring English sources

Exact(5)

Both proteins are post-translationally modified by cell signaling pathways and the PTMs can affect their enzymatic activity or their interaction with the the promoter via p160 coactivators, SRC1, GRIP1/SRC2, or AIB1/SRC3 [32], [32].

The identification of the molecular targets that are affected by SIRT1 phosphorylation, especially at sites modified by cell cycle-dependent kinases like Cdk1, will help to elucidate how changes in the level and activity of SIRT1 affect diverse processes such as growth and longevity in organisms ranging from single-celled yeast to mammals.

The interaction between tumor and immune cells may be modified by cell debris or exosomes, which is produced in response to virus or dsRNA stimulation.

Using the 8B4 antibody (lower panel), PK treatment markedly reduced the immunoreactive signal in both vehicle and hPrP90-231-treated samples, indicating a high PrPC sensitivity to proteolysis that is not modified by cell exposure to hPrP90-231.

Under stress conditions, receptor-interacting protein 1 (Ris1) is modified by cell death receptor-associated proteins, including cellular inhibitors of apoptosis (cIAPs) and cylindromatosis (CYLD), and forms a necrosome with RIP3 and eventually triggers necroptosis.

Similar(55)

Our aim was to establish if human monocyte macrophages internalise nanoparticles and to assess whether nanoparticles are modified by cells following uptake.

These results indicated that, in contrast to the endothelium, HS produced by tumour cells may be modified by cell-surface heparanase (HPA1) or endosulphatase (SULF).

However, an attractor corresponding to each cell type is not invariant against possible changes of surrounding cells, and instead is modified by the cell-cell interaction.

NS1 glycoprotein is anchored in the lumen of endoplasmic reticulum through signal peptidase is cotranslationally modified by host cell signalase.

83 We speculated that detailed analysis of the immune reactions in Cj-EAE that are modified by B-cell depletion might help gaining insight into essential pathogenic mechanisms.

To determine whether the effect of bevacizumab on previously established tumours was modified by VEGF165b, cells were injected as before, and tumours allowed to grow to 4 mm in diameter before treatment with bevacizumab as above.

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